ESTRO 2025 - Abstract Book

S2347

Interdisciplinary – Other

ESTRO 2025

The citation analysis shows the most influential inventions when considering citation impact as: US4930504A (1987): Device for biostimulation of tissue and method for treatment of tissue; WO1995025563A1 (1994): Method and apparatus for therapeutic laser treatment; WO1995019812A1 (1994): Photo-thermal therapeutic device and method. Regarding technology owners, the three companies who own most patents are: Huawei, ZTE Microeletronics, and Philips. Other large players such as Varian and Elekta are in the top 20. Considering geographies, the top three countries where patents were published are: China, Japan, and the USA (Figure 2).

Conclusion There is an exponential growth on the patenting of inventions in radiotherapy. Different countries have led the developments of such technologies over time, with China having by far the highest number of publications in this century. Radiotherapy product innovations are almost exclusively being created in the global North, especially Asia. It also suggests both medical companies and investors should look East when searching for R&D inspiration or for commercial opportunities. Finally, innovations in radiotherapy devices are correlated and often used for diagnosis.

Keywords: Innovation, Medical Devices, Patents

References Pereira, C., Picanco-Castro, V., Covas, D., & Porto, G. (2018). Patent mining and landscaping of emerging recombinant factor VIII through network analysis. Nature Biotechnology, 36(7), 585– 590. https://doi.org/10.1038/nbt.4178