ESTRO 2025 - Abstract Book

S245

Brachytherapy - Gynaecology

ESTRO 2025

Results: Overall, the BRIGHT plan was favoured for 9/10 cases, of which 6 unanimously, and 5 with clinically relevant differences, see Figure 2. The clinical plan was preferred once, with clinical relevance, due to a higher CTV HR -D 90 . However, a corresponding BRIGHT plan existed that outperformed the clinical plan in all aims, indicating that plan navigation could be enhanced. Finally, in 8/30 evaluations, an observer indicated that they would opt not to use the clinical plan for treatment, potentially due to new insights as to what BRIGHT achieved for that patient.

Conclusion: Plans generated using BRIGHT for cervical cancer BT were favoured over clinical plans with clinically relevant differences, regarding EMBRACE-II DVH planning aims, dose distributions, and overall plan choice preferences.

Keywords: Automated treatment planning, Validation study

References: [1] Dickhoff LRM, Scholman RJ, Barten DLJ, Kerkhof EM, Roorda JJ, Bouter A, Velema LA, Stalpers LJA, Pieters BR, Bosman PAN, Alderliesten T. Keeping your best options open with AI-based treatment planning in prostate and cervix brachytherapy. Brachytherapy. 2024; 23(2):188–198. doi:10.1016/j.brachy.2023.10.005.

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Digital Poster The impact of uterine position during brachytherapy on treatment outcomes in patients with cervical cancer Ecem Yigit, Melis Gultekin, Pantea Bayatfard, Sezin Yuce Sari, Fatih Biltekin, Ferah Yildiz Radiation Oncology, Hacettepe University, Faculty of Medicine, Ankara, Turkey

Purpose/Objective: