ESTRO 2025 - Abstract Book

S2700

Physics - Dose calculation algorithms

ESTRO 2025

Conclusion: A closed circulatory system has been established, which comprises the inclusion of patient-specific parameters (FLIP) within a comprehensive blood circulation model (HEDOS) that enables the blood dose quantification during radiotherapy treatments. This is crucial in clinical scenarios where tumors are near vasculature, the surrounding vessel volume is comparable to tumor volume, and total irradiation time is extensive. The ability to accurately report blood dose is essential for attaining a personalized approach in radiotherapy dosimetry.

Keywords: Blood irradiation, dosimetry, radiotherapy

References: [1] GARCÍA-CARDOSA, Marina, et al. FLIP: a novel method for patient-specific dose quantification in circulating blood in large vessels during proton or photon external beam radiotherapy treatments. Physics in Medicine and Biology , 2024.

[2] MA, Liliana E., et al. Aortic 4D flow MRI in 2 minutes using compressed sensing, respiratory controlled adaptive k ‐ space reordering, and inline reconstruction. Magnetic resonance in medicine , 2019, vol. 81, no 6, p. 3675-3690.

[3] BEEKMAN, Chris, et al. A stochastic model of blood flow to calculate blood dose during radiotherapy. Physics in Medicine & Biology , 2023, vol. 68, no 22, p. 225007.