ESTRO 2025 - Abstract Book

S2805

Physics - Dose prediction, optimisation and applications of photon and electron planning

ESTRO 2025

Conclusion: The PreSim method achieves equivalent target coverage with reduced irradiated volumes and mean brain dose compared with margin-based plans. It is not only feasible to boost a probabilistically defined volume to 72Gy without increasing OAR doses, but doing so reduces irradiated volumes and mean brain dose. This seems