ESTRO 2025 - Abstract Book

S2852

Physics - Dose prediction, optimisation and applications of photon and electron planning

ESTRO 2025

were assessed by five professionals, including radiation oncologists, physicists, and dosimetrists, and scored for quality using a 5-point Likert scale.

Results: The automated planning script generated plans within 5-10 minutes. Overall, 83% of the auto-generated plans were clinically acceptable without further modification or minor improvement if time permits. All automated plans met clinical goals by achieving at least 95% coverage of the PTV. The conformity index results were comparable to the clinical plans (p=0.29), and the homogeneity index of PTV demonstrated a minimal increase of 0.01±0.02. The maximum dose of the ipsilateral carotid was comparable to that of the clinical plans (p=0.20). For the contralateral cricoarytenoid, the mean dose was reduced by -0.39±2.16 Gy, while V20Gy showed a decrease of -4.58%±7.15%. Similarly, the normal larynx exhibited a reduction in mean dose by -1.70±2.40 Gy and a V20Gy decrease of - 4.07%±8.40%. Overall, these metrics demonstrated consistency and robustness in the automated plans.

Conclusion: This study demonstrates the proposed automated planning system can produce high-quality plans for larynx SBRT, significantly streamlining the planning process and enhancing consistency in plan quality.

Keywords: Autoplanning, Knowledged-based, Larynx SBRT

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Digital Poster Customizable 3D-printed lung shielding blocks for total body irradiation (TBI) Ethan D. Stolen 1 , Tianming Wu 1 , Lunya Allie 2 , Caleb Song 1 , James J. Sohn 1 1 Department of Radiation and Cellular Oncology, University of Chicago, Chicago, USA. 2 Department of Biology, Washington University in St. Louis, St. Louis, USA