ESTRO 2025 - Abstract Book

S2872

Physics - Dose prediction, optimisation and applications of photon and electron planning

ESTRO 2025

Conclusion: The application of large-scale KB-driven automatic plan optimization using a unique optimization template can generate fully automated plans, comparable to clinical manual plans for both internal and external validation sets. This fully automated method could be potentially relevant in applications for large-scale KB-driven automatic plan optimization, enabling knowledge transfer and supporting the standardization of radiotherapy practices across multiple centers. Further investigations are ongoing to perform clinical assessments of the AMBRA plans over a large scale of institutes and radiation oncologists.

Aknowledgements: current study was supported by a grant from AIRC (IG23150)

Keywords: automated plans; multi-institute KBP model; breast

References: [1] Esposito PG, Castriconi R, Mangili P, Fodor A, Pasetti M, Di Muzio NG, Del Vecchio A, Fiorino C. Virtual Tangential fields Arc Therapy (ViTAT) for whole breast irradiation: Technique optimization and validation. Phys Med. 2020 Sep;77:160-168. doi: 10.1016/j.ejmp.2020.08.011. Epub 2020 Aug 28. PMID: 32866777.

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Digital Poster Dosimetric and Radiobiological Comparison of Hybrid Radiotherapy Technique with IMRT and VMAT for Rectal Cancer Patients Elham Yaghoubvand 1 , Bijan Hashemi 1 , Mohsen Bakhshandeh 2 , Hossein Yahyazadeh 3 , Amin Banaei 1 1 Medical Physics, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran, Islamic Republic of. 2 Radiology Technology, Faculty of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran, Islamic Republic of. 3 Negin Oncology Research Center, Negin Health Care System, Tehran, Iran, Islamic Republic of

Purpose/Objective: The aim of this study is to evaluate the effectiveness of a hybrid radiotherapy technique that combines intensity-