ESTRO 2025 - Abstract Book

S2940

Physics - Dose prediction, optimisation and applications of photon and electron planning

ESTRO 2025

Conclusion: Max_heart_depth is a simple and effective predictor of MHD, strongly influenced by chest-wall and breast anatomy below the IMN PTV. While automated scripting was used in this study, in the clinical setting, max_heart_depth can be manually measured on planning CT scans using the ruler function, requiring only the posterior border of a tangential field. The model predicts MHD within +/-1.6 Gy of a wide tangential plan whereby no compromise to target volume coverage is made, enabling timely, resource-efficient decisions about heart-sparing techniques in left sided breast cancer care.

Keywords: mean heart dose, breast, wide tangents

References: [1] Darby, S. C., et al (2013). Risk of ischemic heart disease in women after radiotherapy for breast cancer. New England Journal of Medicine , 368 (11), 987–998. https://doi.org/10.1056/NEJMoa1209825