ESTRO 2025 - Abstract Book

S2962

Physics - Image acquisition and processing

ESTRO 2025

The analysis showed no clinically significant differences between dose calculated on the calibrated and reconstructed ED map. Figure 2 shows the difference in dose metrics for radiotherapy structures calculated using both ED maps. The median difference across all structures was < 0.17 Gy.

The gamma analysis across all plans was >99.7%, 100% and 100% at 1%/1mm, 2%/2mm and 3%/3mm, respectively.

Conclusion: Photon dose calculations using calibrated and reconstructed ED maps show no clinically significant differences. This suggests that reconstructed ED maps could be used directly for photon radiotherapy dose calculation, across a range of clinical sites.

Keywords: Spectral CT, Dose Calculation, Electron Density

References: [1] Maaß, C., et. al. (2009), IEEE Nuclear Science Symposium Conference Record (NSS/MIC), Orlando, FL, 24-31 October, pp. 3446-3452. doi: 10.1109/NSSMIC.2009.5401784

[2] Ates, O., et al. (2021), British Journal of Radiology, 94(1118), doi: 10.1259/bjr.20200170 [3] Hua, C., et al. (2018), Medical Physics, 45(6), pp. 2486-2497, doi: 10.1002/mp.12903 [4] Zhu, Q., et al. (2024), Radiation Oncology, 19(93), doi: 10.1186/s13014-024-02479-6

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Digital Poster Clinical application of Intelligent 4DCT (i4D): Analysis of image artifact frequency and comparison to conventional 4DCT Lukas Wimmert 1,2,3 , Frederic Madesta 1,2,3 , Hermann Krümpelmann 4 , Katharina Hintelmann 4 , Christian Hofmann 5 , Jannis Dickmann 5 , Tobias Gauer 4 , Rene Werner 1,2,3 1 Institute for Applied Medical Informatics, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 2 Institute of Computational Neuroscience, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 3 Center for Biomedical Artificial Intelligence, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 4 Department of Radiotherapy and Radiation Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. 5 Siemens Healthineers AG, -, Forchheim, Germany