ESTRO 2025 - Abstract Book

S2966

Physics - Image acquisition and processing

ESTRO 2025

evaluation metrics. When the brainstem was incorporated as an additional constraint into the optimization, DSC/DOO of the brainstem contour were significantly higher than those without it as constraint, with regions closer to the brainstem achieving better results.

Conclusion: This study presents an advanced DIR method combining image feature and contour correspondence in head-and neck imaging to improve VBA accuracy. The results demonstrate CPT-DIR ’s superior accuracy, especially when region-specific contour constraints are applied for enhanced results.

Keywords: deformable registration, voxel based analysis, HN

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