ESTRO 2025 - Abstract Book

S2992

Physics - Image acquisition and processing

ESTRO 2025

Results: SNR and CNR values were (Figure 2): • Reference: SNR 20.69, CNR 0.84 • Setup 1: SNR 8.77, CNR 0.22 • Setup 2: SNR 18.09, CNR 0.61 • Setup 3: SNR 18.89, CNR 0.72. • Setup 4: SNR 22.00, CNR 0.74 With RESOLVE, Setup 4 achieved the best quality: SNR 33.94, CNR 1.32, outperforming the reference setup.

Conclusion: This study identifies an optimized MRI coil configuration (Setup 4) for achieving high-quality DTI acquisition under RT constraints in healthy volunteers. These findings demonstrate the feasibility of integrating advanced DTI imaging into RT workflows, paving the way for routine application in brain tumor patients, allowing white matter sparing RT.

Keywords: Diffusion Tensor Imaging, White Matter Sparing, RT

References: [1] S.M. Smith, et al . Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage, 23(S1):208-219, 2004. [2] Schilling KG, et al . Synthesized b0 for diffusion distortion correction (Synb0-DisCo). Magn Reson Imaging. 2019 Dec;64:62-70. doi: 10.1016/j.mri.2019.05.008. [3] Leon Y. Cai, et al . PreQual: An automated pipeline for integrated preprocessing and quality assurance of diffusion weighted MRI images . Magnetic Resonance in Medicine, 2021. [4] Porter DA, et al . High resolution diffusion-weighted imaging using readout-segmented echo-planar imaging, parallel imaging and a two-dimensional navigator-based reacquisition. Magn Reson Med. 2009 Aug;62(2):468-75. doi: 10.1002/mrm.22024.