ESTRO 2025 - Abstract Book

S3008

Physics - Image acquisition and processing

ESTRO 2025

Conclusion: It is possible to detect different materials on PCD-CT images, to correct for contrast agents and high-density materials, opening to the possibility for precise dose calculation while minimizing imaging radiation dose of the patient.

Keywords: Photon-counting CT, Dose calculation

2248

Proffered Paper First-in-human upright CBCT on a C-arm linac: preliminary imaging and positioning results from a prospective clinical trial (ACTRN12623000498695) James C Korte 1,2 , Sulman Rahim 3 , Katrina Woodford 3,4,5 , Nikki Plumridge 4,6 , Susan Harden 4,6 , Neil Wallace 6 , Tsien Fua 4,6 , Yiota Nicolaou 3 , Jack Moller 3 , Ken Nguyen 3 , Elizabeth Pearson 4,7 , Mark Wright 8 , Kate Moodie 4,9 , Tomas Kron 1,4,10 , Nicholas Hardcastle 1,4,10 1 Department of Physical Science, Peter MacCallum Cancer Centre, Melbourne, Australia. 2 Department of Biomedical Engineering, University of Melbourne, Melbourne, Australia. 3 Department of Radiation Therapy, Peter MacCallum Cancer Centre, Melbourne, Australia. 4 Sir Peter MacCallum Department of Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia. 5 Department of Medical Imaging and Radiation Sciences, Monash University, Melbourne, Australia. 6 Department of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Australia. 7 Centre for Health Services and Implementation Research, Peter MacCallum Cancer Centre, Melbourne, Australia. 8 Department of Radiation Mechanical Engineering, Peter MacCallum Cancer Centre, Melbourne, Australia. 9 Department of Cancer Imaging, Peter MacCallum Cancer Centre, Melbourne, Australia. 10 Centre for Medical Radiation Physics, University of Wollongong, Wollongong, Australia Purpose/Objective: Upright patient positioning for radiation therapy may improve the treatment experience for patients who struggle to tolerate the conventional lying position due to pain, breathing, or swallowing issues[1-3]. To offer an alternative position, we developed a rotating radiation therapy chair which integrates with C-arm linacs and facilitates cone beam computed tomography imaging of patients in a seated position[4]. We report preliminary results from a prospective phase 1 trial (ACTRN12623000498695) which is evaluating upright imaging, as a first step towards future upright treatments.