ESTRO 2025 - Abstract Book

S3185

Physics - Inter-fraction motion management and offline adaptive radiotherapy

ESTRO 2025

Conclusion: All methods studied indicate the need for and potential benefit of OAPT. For uncorrected HyperSight CBCTs, extra caution is warranted due to geometry-dependent CT numbers affecting proton dose calculations. Overall, further research on CBCT correction for OAPT is necessary. Keywords: Online adaptive proton therapy, Cone beam CT, CBCT References: [1] Albertini, Francesca, et al. "First clinical implementation of a highly efficient daily online adapted proton therapy (DAPT) workflow." Physics in Medicine and Biology (2024). [2] Sijtsema, Nienke D., et al. "Dose calculation accuracy of a new high-performance ring-gantry CBCT imaging system for prostate and lung cancer patients." Radiotherapy and Oncology (2024). [3] Peters, Nils, et al. "Consensus guide on CT-based prediction of stopping-power ratio using a Hounsfield look-up table for proton therapy." Radiotherapy and Oncology (2023). [4] Bobić, Mislav, et al. "Multi-institutional experimental validation of online adaptive proton therapy workflows." Physics in Medicine & Biology (2024).

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Digital Poster Evaluation of a rotatable head-platform in combination with a surface-guided positioning system Sonja Wegener, Robert Schindhelm, Marcus Zimmermann, Paul Käthner, Kathrin Breuer, Anne Richter, Gary Razinskas, Otto A Sauer Radiation Oncology, University Hospital Würzburg, Würzburg, Germany

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