ESTRO 2025 - Abstract Book

S3259

Physics - Intra-fraction motion management and real-time adaptive radiotherapy

ESTRO 2025

Conclusion: A CBCT-based OART workflow for locoregional lung cancer patients was proposed. It features an automated correction of target misalignments without the need for in-room manual delineation edits, showing potential for treatment margin reduction. This strategy will be clinically introduced in 2025.

Keywords: cone beam CT, lung, online adaptation

References: 1 Schaake EE, Rossi MM, Buikhuisen WA, Burgers JA, Smit AA, Belderbos JS, Sonke JJ. Differential motion between mediastinal lymph nodes and primary tumor in radically irradiated lung cancer patients. Int J Radiat Oncol Biol Phys. 2014 Nov 15;90(4):959-66. doi: 10.1016/j.ijrobp.2014.07.038. Epub 2014 Oct 18. PMID: 25585787. 2 FeASibility of Cbct-guIded oNline Adaptive radioThErapy (FASCINATE), Protocol ID: NCT06691776, March 2023. 3 Software version 5.0.7, Elekta, Stockholm, Sweeden.

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