ESTRO 2025 - Abstract Book

S3327

Physics - Intra-fraction motion management and real-time adaptive radiotherapy

ESTRO 2025

Conclusion: OART allowed for margin reductions, potentially lowering toxicity. However, table shifts to correct for prostate motion during the adaptation increased lymph node inaccuracies. Therefore, further innovations should aim to speed up adaptations.

Keywords: Prostate N+, OART-CBCT, margins

References: [1] Remeijer et al. Leveraging IGRT towards a fast CBCT based online adaptive treatment for prostate plus lymph nodes, Radiother Oncol. 2024 May;194 Supplement 1, S4039-43

[2] M van Herk, P Remeijer, C Rasch, et al. The probability of correct target dosage: Dose-population histograms for deriving treatment margins in radiotherapy, Int J Radiat Oncol Biol Phys, 47 (2000), pp. 1121-1135