ESTRO 2025 - Abstract Book

S345

Brachytherapy - Physics

ESTRO 2025

Conclusion: The use of organ motion simulation could provide a valuable tool for robustness evaluation of HDR brachytherapy treatment plans in cervical cancer, which in the next step should be included in robust treatment planning.

Keywords: Robustness, MR-IGABT, Uncertainties

References: [1] Tanderup K, Hellebust TP, Lang S, Granfeldt J, Pötter R, Lindegaard JC, Kirisits C. Consequences of random and systematic reconstruction uncertainties in 3D image based brachytherapy in cervical cancer. Radiother Oncol. 2008 Nov;89(2):156-63. doi: 10.1016/j.radonc.2008.06.010. Epub 2008 Aug 7. PMID: 18692265. [2] Pötter R, Tanderup K, Kirisits C, et al.. The EMBRACE II study: The outcome and prospect of two decades of evolution within the GEC-ESTRO GYN working group and the EMBRACE studies. Clin Transl Radiat Oncol. 2018 Jan 11;9:48-60