ESTRO 2025 - Abstract Book

S3565

Physics - Optimisation, algorithms and applications for ion beam treatment planning

ESTRO 2025

Figure 2

Conclusion: The code is successfully adapted and pulse structures can be examined in the chemical phase. First results indicate that the yield of H 2 O 2 increases with decreasing pulse widths at the same dose levels, due to the initial positions of the solvated electrons. This leads to an increasing yield of H 2 O 2 with increasing dose rates in the simulations with SBS and IRT,which is in inconsistency with experimental results [4]. Further optimizations to match the simulations to experiments will be implemented and experimentally verified.

Keywords: Flash, Radiolysis, Monte-Carlo Simulations

References: [1] Friedl et al., doi:/10.1002/mp.15184

[2] Chappuis et al., doi:/10.1016/j.ejmp.2023.102601 [3] S. INCERTI et al.,doi:/10.1142/S1793962310000122 [4] Zhang, Stengl, Derksen et al.,doi:/10.1002/mp.17335

4238

Digital Poster Validating radical yield predictions in Monte Carlo simulations of water radiolysis using Fricke solution and sodium nitrate scavenging Natalie Hornik 1,2 , Inessa Sakulov 1,2 , Michelle Meier 1,2 , Larissa Derksen 1,3 , David Weishaar 1 , Robin Erdmann 1 , Ulrike Theiss 3,4,2 , Sebastian Adeberg 3,4,5 , Boris Keil 1,2 , Kai-Thomas Brinkmann 6,2 , Kilian-Simon Baumann 1,2,4 1 Institute of Medical Physics and Radiation Protection, University of Applied Sciences, Giessen, Germany. 2 LOEWE Research Cluster for Advanced Medical Physics in Imaging and Therapy (ADMIT), TH Mittelhessen University of Applied Sciences, Giessen, Germany. 3 Department of Radiotherapy and Radiation Oncology, Marburg Ion-Beam Therapy Center (MIT), Marburg University Hospital, Marburg, Germany. 4 Department of Radiotherapy and Radiation Oncology, Marburg University Hospital, Marburg, Germany. 5 Universitäres Centrum für Tumorerkrankungen (UCT) Frankfurt, University Cancer Center, Marburg, Germany. 6 Second Physics Institute, Justus Liebig University, Giessen, Germany