ESTRO 2025 - Abstract Book

S3574

Physics - Optimisation, algorithms and applications for ion beam treatment planning

ESTRO 2025

Conclusion: The neutron production in tissue during proton therapy was studied for different patients, resulting in distinctly different neutron yields and spatial distributions reflecting patient geometries along the beam paths. This warrants the observed differences to be studied further in a larger patient cohort and utilized for assessment of the NOVOCoDA’s capability for range and dose verification for different patient groups.

Keywords: Proton range verification

4539

Digital Poster AN “eco-friendly” APPROACH FOR PROTON THERAPY PATIENT- AND EXPERIMENT-SPECIFIC DEVICES Isabella Colizzi 1,2 , Ylva Bornhauser 2 , Robert Schäfer 1 , Antony Lomax 1 , David Meer 1 , Serena Psoroulas 3 1 Proton therapy center, PSI, Villigen, Switzerland. 2 Physics, ETH, Zurich, Switzerland. 3 University Hospital, USZ, Zurich, Switzerland Purpose/Objective: The increasing interest in pFLASH radiotherapy has recently sparked a renewed focus on patient-specific devices and passive scattering techniques (PS), which are currently used for treating ocular tumours. The drawback of this technique is the use of (expensive) custom devices, like collimators and compensators, designed for single-use. Our project seeks to improve the existing approach by developing a flexible setup for PS that can be adapted to different needs. In this study, we investigate the reproducibility of this new approach and its feasibility in the complex case of small target structures.

Material/Methods: Each collimating or compensating element consists of 3D-(filament)printed containers of PLA filled with reusable