ESTRO 2025 - Abstract Book

S3577

Physics - Optimisation, algorithms and applications for ion beam treatment planning

ESTRO 2025

compositions compared to the known compositions are less than 1 mm for a 3 cm slab of that material for 200 MeV protons. For 100 MeV protons in homogenous bone and lung exhale the range difference was only 1.2 and 3.7 mm respectively. Conclusion: This work shows that using a PCCT with a base material approach determining tissue mass density and chemical composition even with very few materials can reduce the uncertainties in proton range estimation.

Keywords: Proton range PCCT

References: 1. J Perl, J Shin, J Schümann, B Faddegon, H Paganetti. "TOPAS: an innovative proton Monte Carlo platform for research and clinical applications." Med Phys. 2012 Nov; 39(11):6818-37