ESTRO 2025 - Abstract Book

S3724

Physics - Radiomics, functional and biological imaging and outcome prediction

ESTRO 2025

Conclusion: IVIM hypoxia maps-derived features significantly outperformed those from images and clinical variables for differentiating BCR from non-BCR groups. This study showed that hypoxia mapping could provide better tumor understanding and better differentiation in patients with recurrence after peripheral zone PCa RT.

Keywords: Hypoxia,Prostate,Recurrence

References: [1] Movsas, B. et al. Hypoxia in human prostate carcinoma: an Eppendorf PO2 study. Am J Clin Oncol. 2001 [2] Le Bihan, D. et al. Separation of diffusion and perfusion in intravoxel incoherent motion MR imaging. Radiology. 1988 [3] Wang, R. et al. Comparative study of diagnostic value between IVIM and DWI for prostate cancer at 3.0 T magnetic resonance. Chin J Acad Radiol. (2021) [4] Chen, Z. et al. The performance of intravoxel-incoherent motion diffusion-weighted imaging derived hypoxia for the risk stratification of prostate cancer in peripheral zone. Eur J Radiol. 2020 [5] Hompland, T. et al. Combined MR Imaging of Oxygen Consumption and Supply Reveals Tumor Hypoxia and Aggressiveness in Prostate Cancer Patients. Cancer Res. 2018

709

Digital Poster Developing A Novel Time-to-Event Dosiomics Model to Predict Treatment Failure in NSCLC Patients Receiving Stereotactic Body Radiotherapy Shuo Wang 1 , Ashok Bhandari 1 , Kurtis Johnson 1 , Kyuhak Oh 1 , Fang Yu 2 , Yu Lei 1 , Shankar Sapkota 3 , Sumin Zhou 1 , Michael J Baine 1 , Chi Lin 1 , Chi Zhang 1 1 Radiation Oncology, University of Nebraska Medical Center, Omaha, USA. 2 Biostatistics, University of Nebraska Medical Center, Omaha, USA. 3 Medical Physics, Creighton University, Omaha, USA