ESTRO 2025 - Abstract Book

S3763

Physics - Radiomics, functional and biological imaging and outcome prediction

ESTRO 2025

Conclusion: ADC values in rectal cancer showed reasonable repeatability without application of an ultrasound gel filling. Reproducibility was worse when comparing images with and without rectal filling, stressed by a clear ADC bias. However, multicenter studies with more patients are necessary to validate these results.

Keywords: diffusion-weighted MRI, repeatability, MR-Linac

References: [1] Drago SG, Maino C, Giandola TP, Franco PN, Corso R, Talei Franzesi C, et al. Correlations between Apparent Diffusion Coefficient (ADC) and Prognosis in Patients with Locally Advanced Rectal Cancer. Life (Basel).2024;14. [2] Lo Russo M, Nachbar M, Barry A, Bhide S, Chang A, Hall W, et al. Impact of endorectal filling on interobserver variability of MRI based rectal primary tumor delineation. Clinical and Translational Radiation Oncology.2023;38:1-5. [3] Shukla-Dave A, Obuchowski NA, Chenevert TL, Jambawalikar S, Schwartz LH, Malyarenko D, et al. Quantitative imaging biomarkers alliance (QIBA) recommendations for improved precision of DWI and DCE-MRI derived biomarkers in multicenter oncology trials. J Magn Reson Imaging.2019;49:e101-e21.

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Digital Poster Deep learning-based recurrence prediction of nasopharyngeal carcinoma ziwei Li 1 , weigang Hu 2 , jiazhou Wang 2 , yue Zou 1 , zhenhao Li 1 , xiaojie Yin 1 1 Radiation Oncology, Fudan University Shanghai Cancer Center, shanghai, China. 2 Radiation Oncology, Fudan Univers, shanghai, China

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