ESTRO 2025 - Abstract Book
S3814
Physics - Radiomics, functional and biological imaging and outcome prediction
ESTRO 2025
Conclusion: This study demonstrates that cardiac substructure models offer superior predictive power and robustness over WH models for hs-cTnT elevation in NSCLC radiotherapy, supporting their utility in cardiotoxicity risk assessment.
Keywords: Cardiotoxicity, logistic regression, LAD
References: 1. Xu T, et al. Assessment of Prognostic Value of High-Sensitivity Cardiac Troponin T for Early Prediction of Chemoradiation Therapy-Induced Cardiotoxicity in Patients with Non-Small Cell Lung Cancer: A Secondary Analysis of a Prospective Randomized Trial. International Journal of Radiation Oncology*Biology*Physics . 2021;111(4):907-916. 2. Liao Z, et al. Bayesian Adaptive Randomization Trial of Passive Scattering Proton Therapy and Intensity-Modulated Photon Radiotherapy for Locally Advanced Non–Small-Cell Lung Cancer. JCO . 2018;36(18):1813-1822. 3. Chen X, Mumme RP, Corrigan KL, et al. Deep learning–based automatic segmentation of cardiac substructures for lung cancers. Radiotherapy and Oncology . 2024;191:110061.
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