ESTRO 2025 - Abstract Book

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Brachytherapy - Urology

ESTRO 2025

Conclusion: In constrast to other radiation techniques, lower PSA nadir value and a delayed time to PSA nadir after LDR-BT evidence favorable outcomes in terms of BF.

Keywords: PSA-nadir, Low-Dose-Rate Brachytherapy

References: Burchardt W, Skowronek J. Time to PSA rise differentiates the PSA bounce after HDR and LDR brachytherapy of prostate cancer. J Contemp Brachytherapy. 2018 Feb;10(1):1-9. doi: 10.5114/jcb.2018.73786. Nakai Y, Tanaka N. Prostate-specific antigen (PSA) nadir and experience of PSA bounce after low-dose-rate brachytherapy for prostate cancer predicts clinical failure. Brachytherapy. 2024 Oct 4:S1538-4721(24)00395-7. doi: 10.1016/j.brachy.2024.09.003. Kishan AU, Wang PC. SBRT and HDR brachytherapy produce lower PSA nadirs and different PSA decay patterns than conventionally fractionated IMRT in patients with low- or intermediate-risk prostate cancer. Pract Radiat Oncol. 2016 Jul-Aug;6(4):268-275. doi: 10.1016/j.prro.2015.11.002.

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Digital Poster Physical and biological (EQD 2 ) dose comparisons in various prostate radiation regimens Joerg Zimmermann 1 , Mandy Zimmermann 2,1 , Florian Würschmidt 3 , Nils H. Nicolay 4 , Christos Moustakis 4 1 Brachytherapy, Praxiszentrum Alstertal, Hamburg, Germany. 2 Medical Physics, Radiologische Allianz, Hamburg, Germany. 3 Radiation Oncology, Radiologische Allianz, Hamburg, Germany. 4 Radiation Oncology, University Hospital, Leipzig, Germany