ESTRO 2025 - Abstract Book

S3932

Radiobiology - Normal tissue radiobiology

ESTRO 2025

Conclusion: MoO x alleviates radiation-induced enteritis safely and effectively by consuming endogenous H 2 S, and might serve as a promising radioprotectant against ionizing irradiation.

Keywords: radiation-induced enteritis, hydrogen sulfide

References: 1.Murphy, J. D. et al. A Dosimetric Model of Duodenal Toxicity After Stereotactic Body Radiotherapy for Pancreatic Cancer. International Journal of Radiation Oncology*Biology*Physics 78 , 1420–1426 (2010). 2.Cameron, S. et al. Radiation-induced damage in different segments of the rat intestine after external beam irradiation of the liver. Experimental and Molecular Pathology 92 , 243–258 (2012). 3.Takatori, K. et al. Upper gastrointestinal complications associated with gemcitabine-concurrent proton radiotherapy for inoperable pancreatic cancer. J Gastroenterol 49 , 1074–1080 (2014).

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