ESTRO 2025 - Abstract Book

S4079

RTT - Patient care, preparation, immobilisation and IGRT verification protocols

ESTRO 2025

Conclusion: MANIV-BH significantly improves CBCT quality and facilitates IGRT for liver SABR compared to FB. Operator variability in IGRT was similar across techniques, except in the superior-inferior direction, supporting MANIV-BH. MANIV-BH enhances liver SABR treatments by breathing-related tumour motion and refining per-treatment CBCT images and IGRT. This enables more consistent and accurate treatments, further supporting innovative techniques like adaptive RT that relies on high image quality.

Keywords: Liver SABR, Mechanical Breath-Hold, IGRT

References: 1. Vogel, A., et al., Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow up. Ann Oncol, 2018. 29 (Suppl 4): p. iv238-iv255. 2. Vander Veken, L., et al., Lung and Liver Stereotactic Body Radiation Therapy During Mechanically Assisted Deep Inspiration Breath-Holds: A Prospective Feasibility Trial. Advances in Radiation Oncology, 2024. 9 (9): p. 101563.