ESTRO 2025 - Abstract Book

S4156

RTT - Patient experience and quality of life

ESTRO 2025

Patients and carers shared any cognitive and physical symptoms they experienced after brain radiotherapy, along with views on the focus of future research. They were consulted on the length and interval of serial testing as well as its delivery format. Results: Radiotherapy had impacted the cognition and Quality-of-Life of all contributors. Further research is required to quantify the side-effects of SRS and ultimately minimise them. Cognitive status and Quality-of-Life will be captured via the Montreal Cognitive Assessment and the EORTC QLQ-C30 and BN20 questionnaires. The patient population will be patients with brain metastases and meningiomas that receive SRS. Testing will be restricted to 30 minutes as per PPI recommendations. It will be offered face-to-face, in hospital, at patients’ homes as well as online. It proved challenging for patients and carers to participate in discussion groups. The original PPI plans were amended to accommodate the physical and mental needs of patients/carers, and one-to-one discussions and online questionnaires were implemented as an alternative. Co-production was not achieved with our patient population. However, this should not diminish either the input or the impact our contributors had on the study protocol design. Conclusion: Meticulous considerations are required to ensure involvement methods are suitable for vulnerable cancer populations. It is essential to be flexible and adaptable with draft PPI plans in order to achieve meaningful contributions. People with lived experiences of brain radiotherapy positively shaped the protocol of the CoDeB-Rad study.

Keywords: PPIE, Cognitive Decline, QoL

References: 1. Arnstein, S. R. (1969) ‘A Ladder Of Citizen Participation’, Journal of the American Institute of Planners , 35(4), pp. 216– 224. doi: 10.1080/01944366908977225. 2. Involvement-Engagement-Ladder.v2. [cited 2024 Apr 29]; Available from: https://www.learningforinvolvement.org.uk/wp-content/uploads/2024/03/Involvement-Engagement-Ladder.v2.pdf

1030

Proffered Paper Impact of radiotherapy on quality of life reported by the elderly patient.

Pilar Maria Samper Ots 1 , Miriam Palomas Moreno 2 , Dolores de las Peñas Cabrera 1 , Lucia Tueros Farfan 3 , Lidia Gómez Perea 4 , Carla Sánchez Cortés 5 , Andrea Bobo Jaureguizar 6 , Carolina de la Pinta Alonso 7 , Jose Luis Monroy Antón 8 1 Radiation Oncology, H. Universitario Rey Juan Carlos, Móstoles, Spain. 2 Radiation Oncology, H. Universitario Regional de Málaga, Málaga, Spain. 3 Radiation Oncology, H. Universitario Arnau de Vilanova, Lérida, Spain. 4 Radiation Oncology, H. Nuestra Señora de la Candelaria, Tenerife, Spain. 5 Radiation Oncology, H. Universitario de Toledo, Toledo, Spain. 6 Radiation Oncology, H. Ruber Internacional, Madrid, Spain. 7 Radiation Oncology, H. Universitario Ramón y Cajal, Madrid, Spain. 8 Radiation Oncology, H. Universitario de Alcira, Alzira, Spain

Purpose/Objective: To determine the impact of radical radiotherapy (RT) treatment on the quality of life reported by the elderly patient.

Material/Methods: A prospective multicenter study was conducted in 8 national centers. Patients over 70 years old, who had an indication for radical RT were included. All patients were initially assessed with the G8 scale, ECOG, Nutriscore, SARC_F and