ESTRO 2025 - Abstract Book

S4165

RTT - Patient experience and quality of life

ESTRO 2025

12.6). All those patients achieved the MANIV-BH after the coaching session. For the ease of execution, patients gave a median score of 8.0 (IQR: 2.5) after the coaching session and 9.5 (IQR: 2.7) after the treatment. The median score for the ease of understanding was 8.5 (IQR: 3.5). Comfort during the coaching and radiotherapy sessions was rated 8.0 (IQR:3.0) and 8.5 (IQR: 4.0), respectively. Four patients (33%) reported stress before the coaching session, compared to only one patient before the SABR sessions. However, the McNemar test showed no significant difference ( p = 0.25). Finally, 11/12 patients (92%) stated they would be willing to undergo this technique again if necessary. Conclusion: This study highlights the positive experiences of patients with MANIV-BH. The high scores for ease of execution, understanding, and comfort, along with the willingness of most patients to repeat the procedure underscore the good tolerance levels achieved by our approach associating a physiotherapist to the radiotherapy team. By fostering a multidisciplinary environment, we can improve the implementation and effectiveness of innovative techniques like MANIV in clinical practice.

Keywords: Breath-holds, ventilation, Patient experience

References:

1. Van Ooteghem, G., et al., Mechanically-assisted and non-invasive ventilation for radiation therapy: A safe technique to regularize and modulate internal tumour motion. Radiother Oncol, 2019. 141 : p. 283-291. 2. Vander Veken, L., et al., Voluntary versus mechanically-induced deep inspiration breath-hold for left breast cancer: A randomized controlled trial. Radiother Oncol, 2023. 183 : p. 109598. 3. Vander Veken, L., et al., Lung and Liver Stereotactic Body Radiation Therapy During Mechanically Assisted Deep Inspiration Breath-Holds: A Prospective Feasibility Trial. Adv Radiat Oncol, 2024. 9 (9): p. 101563.

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Digital Poster Patient perspectives of liver SABR: a qualitative study.

Matthew R Beasley 1,2 , Carole Burnett 1,2,3 , Vivian P Cosgrove 4 , Ann M Henry 5,6 , Louise J Murray 5,6 , Janine Bestall 7 1 Radiotherapy, Leeds Cancer Centre, St. James’s University Hospital, Leeds, United Kingdom. 2 Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom. 3 NIHR Leeds Biomedical Research Centre, NIHR Leeds Biomedical Research Centre, Leeds, United Kingdom. 4 Medical Physics and Engineering, Leeds Cancer Centre, St. James’s University Hospital, Leeds, United Kingdom. 5 Clinical Oncology, Leeds Cancer Centre, St. James’s University Hospital, Leeds, United Kingdom. 6 School of Medicine, University of Leeds, Leeds, United Kingdom. 7 Leeds Institute of Health Sciences, University of Leeds, Leeds, United Kingdom Purpose/Objective: Acknowledging the lack of qualitative data regarding patients undergoing liver stereotactic ablative body radiotherapy (SABR), this study explored patient experiences to identify themes that may inform improvements in patient support and treatment processes. Material/Methods: Ten patients undergoing liver SABR participated in semi-structured interviews via purposeful sampling. Interviews took place towards the end or within a week of treatment completion and were scheduled at convenient times and locations for the participants (online or in person). The Health Research Authority (23/WM/0070) provided ethical approval. Using a pre-designed topic guide with prompts, discussions focused on radiotherapy planning, treatment procedures, development areas, and messages for future patients. Interviews were recorded, transcribed verbatim, and analysed using the framework method. 1,2