ESTRO 2025 - Abstract Book

S477

Clinical - Breast

ESTRO 2025

hypertension (16%) being the most common. Responders reported high satisfactions (76%) or satisfaction (11%) with the cosmetic outcome of the breast, leaving 14% dissatisfied or very dissatisfied. Sensory disturbances in the breast area, axilla, arm, or hand were reported by 278 (33%) of the survivors, with the breast area (20%) or axilla (13%) being the most common. Furthermore, 633 (75%) reported pain within the last 7 days, with the shoulder (34%) and back (35%) being the most common. Of these, 471 (75%) survivors believed that their pain was related to other circumstances than BC treatment. With levels varying from moderate to severe, 281 (33%) survivors reported insomnia, 166 (19%) fear of cancer recurrence, 98 (12%) cognitive impairment, and 62 (6%) depressive symptoms within the last 7 days (Table 1).

Conclusion: Self-reported satisfaction with the results of surgery and RT was high. General biopsychosocial late effects were common in both cohorts even more than ten years after primary treatment.

Keywords: Breast Cancer, online reporting, late-effects

References: [1] Offersen B V, Alsner J, Nielsen HM, Jakobsen EH, Nielsen MH, Krause M, et al. Hypofractionated Versus Standard Fractionated Radiotherapy in Patients with Early Breast Cancer or Ductal Carcinoma in Situ in a Randomized Phase III Trial: The DBCG HYPO Trial. J Clin Oncol 2020;38:3615–36 [2] Offersen BV, Alsner J, Nielsen HM, Jakobsen EH, Nielsen MH, Stenbygaard L et al. Partial Breast Irradiation Versus Whole Breast Irradiation for Early Breast Cancer Patients in a Randomized Phase III Trial: The Danish Breast Cancer Group Partial Breast Irradiation Trial. J Clin Oncol 2022;40:4189-97