ESTRO 2025 - Abstract Book

S798

Clinical - Gynaecology

ESTRO 2025

of late severe gastrointestinal toxicities were 7.4% and 0.0% in the whole- and individualized-uterine groups, respectively ( p =0.009).

Conclusion: Individualized-uterine radiotherapy achieved favorable clinical outcomes and less severe acute or late gastrointestinal toxicity compared to whole-uterine radiotherapy. These findings suggest that individualized-uterine design may optimize therapeutic ratio of radiotherapy in locally advanced cervical cancer.

Keywords: Cervical cancer; IMRT; Individualized uterine.

References: 1. Van Damme A, Tummers P, De Visschere P, et al. Exclusion of non-Involved uterus from the target volume (EXIT trial): An individualized treatment for locally advanced cervical cancer using modern radiotherapy and imaging techniques followed by completion surgery. Clin Transl Radiat Oncol. 2024;47:100793. 2. Hui C, Ewongwo A, Mendoza MG, et al. Less than whole uterus irradiation for patients with locally advanced cervical cancer. Radiother Oncol. 2024;194:110199.

926

Digital Poster A systematic review of the impact of pelvic radiotherapy on the sexual health of gynecological cancer patients Lara Hathout 1 , Yingting Zhang 2 , Emma Charlotte Fields 3 , Stella Lymberis 4 , Zohaib Sherwani 1 , Irina Vergalasova 1 1 Radiation Oncology, Rutgers Cancer Institute, New Brunswick, USA. 2 Department of Medicine, Robert Wood Johnson Library of the Health Sciences, New Brunswick, USA. 3 Radiation Oncology, Virginia Commonwealth University Health System, Richmond, USA. 4 Radiation Oncology, NYU Langone Health, New York City, USA