ESTRO 2025 - Abstract Book

S830

Clinical - Gynaecology

ESTRO 2025

Conclusion: These preliminary results suggest that early tumor reduction, particularly by fraction 10, may be a predictive marker for final treatment response in cervical cancer patients. This will open the possibility for early personalized treatment adaptation. Further studies with larger cohorts are needed to confirm these findings.

Keywords: cervical cancer, MR-Linac, tumor evolution

References: [1] Lizano, M., Carrillo-García, A., de la Cruz-Hernández, E., Castro-Muñoz, L. J., & Contreras-Paredes, A. (2024). Promising predictive molecular biomarkers for cervical cancer: A review. International Journal of Molecular Medicine . https://doi.org/10.3892/ijmm.2024.5374

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Mini-Oral Accurate GTV Delineation and Radiomics-Based Recurrence Prediction in Cervical Cancer Using Pre Treatment MRI Jie Chen 1 , Jie Z Mo 2 , Jue Pan 1 , Lin S Liu 1 , Che Wang 1 , Jin Wang 1 , Yu Liang 1 , Yu J Qiao 1 , Yi J Yang 1 , Jiao M Cai 1 , Cheng L Jia 2 , Lu J Ma 1 1 Department of Radiation Oncology, First Affiliated Hospital of Xi’an Jiaotong University, Xi’an, China. 2 Research cooperation department, Shenzhen United Imaging Research Institute of Innovative Medical Equipment, Shenzhen, China Purpose/Objective: Tumor recurrence is one of the high-risk lethal factors for cervical cancer patients. Accurately delineating the primary gross tumor volume (GTV) on pre-treatment magnetic resonance (MR) images for recurrence prediction is of significant importance in developing personalized prognostic management strategies for cervical cancer patients.