ESTRO 2025 - Abstract Book

S936

Clinical – Head & neck

ESTRO 2025

Conclusion: Re-PT demonstrated promising local control and survival rates. Non-conventional fractionation including SBPT regimens especially in small tumor volume may offer improved outcomes, though larger studies are warranted. However, significant toxicities highlight the importance of careful patient selection and long-term monitoring.

Keywords: proton, reirradiation, head and neck cancer

524

Mini-Oral Oncological outcomes after stereotactic body radiotherapy of lung metastases in patients with oligometastatic head-and-neck squamous cell carcinoma Alexander Rühle 1,2 , Samuel Vorbach 3 , Felix Ehret 4 , Ahmed Allam Mohamed 5 , Saranda Thaqi 2 , Alexander Fabian 6 , Thomas Weissmann 7 , Sophia Drabke 8 , Esmée Looman 9 , Maria Waltenberger 10 , Kaja Dehl 11 , Susanne Rogers 12 , Ahmed Gawish 13 , Jan-Niklas Becker 14 , Johannes Kraft 15 , Rainer J Klement 16 , Richard Partl 17 , Michael J Eble 5 , Nils H Nicolay 1 , Christos Moustakis 1 , Ute Ganswindt 3 , Oliver Blanck 6 , Andrea Wittig-Sauersein 15 , Panagiotis Balermpas 9 , Franziska Nägler 1 1 Department of Radiation Oncology, University of Leipzig Medical Center, Leipzig, Germany. 2 Department of Radiation Oncology, Medical Center – University of Freiburg, Faculty of Medicine, University of Freiburg, German Cancer Consortium (DKTK), partner site DKTK-Freiburg, Freiburg, Germany. 3 Department of Radiation Oncology, Medical University of Innsbruck, Innsbruck, Austria. 4 Department of Radiation Oncology, Charité – Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany. 5 Department of Radiation Oncology, RWTH Aachen University Hospital, Aachen, Germany. 6 Department of Radiation Oncology, University Hospital Schleswig-Holstein and Saphir Radiosurgery Center Northern Germany, Kiel, Germany. 7 Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Erlangen, Germany. 8 Department of Radiation Oncology, University Medical Center Mainz, Mainz, Germany. 9 Department of Radiation Oncology, University of Zurich, Zurich, Switzerland. 10 Department of Radiation Oncology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany. 11 Department of Radiation Oncology, University Hospital Hamburg-Eppendorf, Hamburg, Germany. 12 Radio-Onkologie-Zentrum Mittelland, Kantonsspital Aarau, Aarau, Switzerland. 13 Department of Radiation Oncology, University Medical Center Giessen-Marburg, Marburg, Germany. 14 Department of Radiotherapy and Special Oncology, Medical School Hannover, Hannover, Germany. 15 Department for Radiotherapy and Radiation Oncology, University of Würzburg, Würzburg, Germany. 16 Department of Radiotherapy and Radiation Oncology, Leopoldina Hospital Schweinfurt, Schweinfurt, Germany. 17 Department of Radiation Oncology, Medical University of Graz, Graz, Austria