ESTRO 35 Programme book

Symposium SBRT IN LUNG - CHOICES AND THEIR IMPACT ON RELATED UNCERTAINTIES 08:45 - 10:00 | ROOM 1

MONDAY 2 MAY 2016

This symposium will review current practice of SBRT in lung from different angles, i.e. view of medical physics, radiation oncology and radiation biology. The impact of dose calculation and fluence optimiza- tion on outcome will be addressed, together with aspects of treatment plan robustness against motion. Furthermore dose effect relationships for local tumor control in NSCLC will be presented, and the pitfalls of current treatment/prescription protocols with in-homogeneous dose distributions within the PTV. In this context also the impact of dose profiles on the effective dose delivered to the GTV will be discussed. Furthermore, the balance between maximizing local tumor and minimizing the risk of toxicity will be covered in this symposium. The different “Rs” of radiobiology will be reviewed together with limitations of the LQ model at high doses, since this is often applied for relating morbidity endpoints with current knowledge on toxicity. Finally, new aspects of “high dose biology” will be presented.

Chair: W. Lechner (Austria) Co-chair: S. Clemente (Italy)

08:45 > Dosimetric aspects and robustness in treatment plan optimisation of small tumours Speaker: A. Ahnesjö (Sweden)

SP-0411

09:10 > Does the prescription isodose matter? Speaker: M. Guckenberger (Switzerland)

SP-0412

09:35 > To use or not to use the LQ model at “high” radiation doses Speaker: W. Dörr (Austria)

SP-0413

Proffered Papers PHYSICS 10: FUNCTIONAL IMAGING I 08:45 - 10:00 | ROOM 500 Chair: M. Philippens (The Netherlands) Chair: S. Agostinelli (Italy)

08:45 > Assessing 4DCT-ventilation as a functional imaging modality for thora- cic radiation therapy Y. Vinogradskiy (USA), L. Schubert, T. Waxweiler, Q. Diot, R. Castillo,

E. Castillo, T. Guerrero, C. Rusthoven, L.E. Gaspar, B. Kavanagh, M. Miften OC-0414

08:55 > The effect of breathing motion on CT radiomics feature extraction in oesophageal cancer R.T.H.M. Larue (The Netherlands), L. Van De Voorde, R.T.H. Leijenaar, M. Berbée, M.N. Sosef, W.J.C. Van Elmpt, P. Lambin

OC-0415

INTERDISCIPLINARY RADIOBIOLOGY

CLINICAL BRACHYTHERAPY PHYSICS

RTT

YOUNG

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