ESTRO 36 Abstract Book

S1000 ESTRO 36 2017 _______________________________________________________________________________________________

Website A scored 88 out of 141 or 62.41% on the LIDA tool, someway less than the other 3 popular patient websites. Website A scored highly in consistency of layout, search function and website accessibility, but scored less well for reliability (1 out of 27). Other issues identified with Website A included clarity of information and user interaction. In addition,website A had readability issues, with some content written at a level higher than advised by guidelines. This will impede those with low literacy from effectively using the website. Conclusion Website A scored lowest of the four websites as a result of issues relating to the reliability of the website. This issue is easy to address, and acting on recommendations from this research, would bring the website in line with other recognised cancer patient information websites, in relation to usability.It is important to remember that the studied websites, while all related to cancer information, are not directly comparable in that they are not specific to radiotherapy, the size of the organisation, the traffic to the site or the country of the sites origin. However steps can be taken as a result of this study to improve the usability of Website A, allowing for greater empowerment of patients through knowledge acquisition which may ultimately lead to improved clinical outcomes. EP-1856 The impact of waiting time on survival of Lung Stereotactic Ablative Body Radiotherapy patients Y. Tsang 1 , P. Nariyangadu 2 , N. Shah 3 , P. Ostler 3 , P. Hoskin 3 1 Mount Vernon Hospital, Radiotherapy, Northwood Middlesex, United Kingdom 2 Mount Vernon Hospital, Radiotherapy Physics, Northwood Middlesex, United Kingdom 3 Mount Vernon Hospital, Clinical Oncology, Northwood Middlesex, United Kingdom Purpose or Objective The introduction of Stereotactic Ablative Body Radiotherapy (SABR) has led to a rapid change in treatment utilization in elderly patients with early stage non-small cell lung carcinoma (NSCLC). This study aims to investigate the impact of waiting time on lung SABR A consultant radiographer has been appointed to lead our institution’s SABR service since April 2014. The post holder was expected to streamline the patient pathways that still deliver high quality services but in more resourceful and innovative ways including radiographer led target volume delineations and consent. Between 2011 and 2015, 105 NSCLC patients were treated with SABR. A retrospective review was done to determine the relationship between overall survival (OS) and intervals between decision to treat and treatment start date (INT). Medians were used to split the distribution of INT into two groups: below and above median. Survival curves for each group were compared using a log rank test. Similar analysis was undertaken comparing patients who were treated before and after the appointment of the consultant radiographer. Results The median age was 73.9 years (range: 53.0-92.9) and median follow-up was 30.8 months (range: 14.9-74.6). For all patients the median OS was 20.7 months (95%CI: 15.4- 26.0) and INT was 1.0 months (range: 0.1-6.9) respectively. No significant difference in OS was found between the below and above median groups (p=0.46). The median waiting time has been shortened from 1.4 months to 0.6 months (p<0.05) since the joining of the consultant radiographer at our institution although no effect on OS (p= 0.13) is found. Conclusion It’s suggested that the waiting time has been shortened since the appointment of the consultant radiographer. treatment outcomes. Material and Methods

However no significant effect on OS has been seen. This is contrary to published data using conventional radiotherapy. The short overall time for SABR may be compensating for the difference in waiting time to start. The numbers in this study are small and a significant difference may emerge with a larger cohort. EP-1857 Radiotherapy impairs on the bonding system in primary teeth A. Queiroz 1 , T. Mellara 1 , P. Nelson-Filho 1 , J. Arid 1 , J. Romano 1 , H. Oliveira 2 , R. Palma-Dibb 1 1 University of São Paulo - School of Dentistry of Ribeirão Preto, Department of Pediatric Dentistry, RIBEIRAO PRETO, Brazil 2 University of São Paulo - School of Medicine of Ribeirão Preto, Department of Medical Clinics, RIBEIRAO PRETO, Brazil Purpose or Objective When radiotherapy (RT) is performed in the head and neck region, it could lead to structural alteration in enamel and dentin that could influence the behavior of the bonding agents. The present study aimed to evaluate whether the RT interferes in the bonding o two adhesive systems (Clearfil SE Bond e Adper TM Single Bond 2) to enamel (E) and dentin (D) of primary teeth, in different times (before and after RT). Material and Methods Sixty primary molars were cut in a total of 120 fragments of enamel and 120 of dentin, which after the surface polishing were randomly divided into 4 groups (n=30/group): G1 (control) – enamel and dentin without RT + restorative procedures; G2 - restorative procedures performed before RT; G3 - restorative procedures performed after RT; and G4 - restorative procedures performed 6 months after RT. Each one of the groups was then divided into 2 subgroups: subgroup A – using the etch- rinse Adper TM Single Bond 2; and subgroup B – using the self-etch Clearfil SE Bond. The specimens were irradiated in dose fractions of 2 Gy, for 5 consecutive days, until reaching the final dose of 60Gy, in a total of 30 fractions, during 6 weeks. The restorative procedures were done using the Z350 composite, and for standardization of the restorations a matrix was used, so the specimens all presented 4 mm height and 2 mm of diameter. The specimens were submitted to the shear bond strength test (load of 50 kgf and speed of 0.5 mm/minute), the result was obtained in N and then transformed to Mpa. The fracture pattern was analyzed in a confocal microscopy (MC). Five specimens of enamel and 5 of dentin were chosen to the morphological analyzes also by MC, those specimens were evaluated every 10 Gy. As for the bonding interface 3 specimens of each group were chosen, and prepared for scanning electron microscopy (SEM). Enamel and dentin were evaluated separately, data was analyzed by the ANOVA and Post Test Tukey (p<0.05). Significance level was 5%. Results It could be observed that for both substrates the Clearfil SE Bond (E: 20.19 MPa; D: 17.61 MPa) was statically superior than Single Bond (E: 17.21 MPa; D: 15.45 MPa) (p<0.05). As for the time of restoration, group 2 had the worst results, in both enamel and dentin. It was observed that that radiation affected negatively the bonding in enamel and dentin (p<0.05), however, in the group 4 no alterations were observed (p<0.05). The predominant fracture pattern was the adhesive, which had raised its prevalence according to the radiation. In the MC analyses there were morphological alteration in enamel and dentin after the cumulative doses of 40 Gy. It was observed, by SEM, tags formations and alterations on the hybrid layer. Conclusion It could be concluded that RT had affected the morphological surface of enamel and dentin, and that it affected the adhesion of the bonding systems, indicating