ESTRO 36 Abstract Book

S392 ESTRO 36 2017 _______________________________________________________________________________________________

Rheumatology- Allergy and Immunology-, Taoyuan, Taiwan

with their email address, profession and hospital affiliation, while the IP address of the computer from which the website is accessed is used to track the user’s geographic location. Google Analytics and Mixpanel were employed to track the number and duration of each page view, which was linked to the unique registered user. Descriptive statistics were reported, including frequency of repeat use (primary endpoint) defined as the ratio of users that accessed the website on two different days divided by the total number of registered users. Users in the top quintile were further characterized by profession and geographic location. Results eContour has 2,616 registered users, of which most (60%) are radiation oncologists (1,092 practicing physicians and 459 residents). Other users include dosimetrists (16%), physicists (9%), radiation therapists (5%), and medical students (5%). Registered users represent 81 countries, with the majority (56%) of users located in the US (see Figure for map). Overall rate of repeat use was 49%, with residents most likely to return to the site (63%) and physicists least likely (36%). Repeat users visited the site on up to 58 different days during the dissemination period, with residents visiting a mean 6.6 different days and practicing physicians visiting a mean 5.4 different days. Users in the top quintile were primarily physicians (69%) and from the US (67%). Of 33 posted cases in H&N, GI, GYN, GU and lymphoma, the most frequently viewed disease site was H&N (8,171 case views) followed by GI (4,665 case views) and the most frequently viewed cases were nasopharynx, pre-op rectal, pre-op esophageal, anal, post-op endometrial, and intact prostate cancer, each with over 1,000 page views. Users viewed each case page for an average of 3.7 minutes.

Purpose or Objective For young female cancer survivors who ever received radiotherapy, adverse pregnant outcomes are serious questions not only for themselves but also for their babies. The purpose of this study was to estimate the risks of adverse foetal-neonatal outcomes in female cancer patients received radiotherapy (RT) compared with women without malignancies. Material and Methods We identified 2,350,335 singleton pregnancies using Taiwan National Health Insurance Database and Taiwan Birth Registry between 2001 and 2012, of which 607 pregnancies were in female cancer patients with RT. Odds ratios (ORs) and 95% confidence intervals (CIs) for foetal- neonatal outcomes were estimated using generalized estimating equation model adjusted by maternal age, income, occupation, Charlson comorbidity index, urbanization, infant sex and birth of year. Results From 2001 to 2012, the mean age at pregnancy of female cancer patients received radiotherapy was 33.5 years old. There were no significant increasing risks with an adjusted OR (95% CIs) of 0.50 (0.21-1.21) for stillbirth, 0.75 (0.55- 1.02) for low birth weight, 0.6 (0.45-0.80) for prematurity, 0.97 (0.75-1.27) for small for gestational age, 0.82 (0.65- 1.04) for large for gestational age, 0.98 (0.69-1.38) for foetal distress, 1.21 (0.92-1.59) for any foetal abnormalities, 1.36 (0.56-3.29) for central nervous system malformation, 1.39 (0.62-3.09) for chromosomal abnormalities, and 1.20 (0.77-1.87) for other/unspecified abnormalities. The risks of Apgar score < 7 in 1 minute and in 5 minutes were not significant increased with ORs of 0.71 (0.43-1.18) and 0.62 (0.20-1.94). Conclusion For female cancer patients who received radiotherapy, there were no significant increasing their adverse birth outcomes compared to women without malignancies. PO-0753 Radiation therapy and outcome in cancer patients with acute venous thromboembolism. J.B. Guy 1 , L. Bertoletti 2 , N. Magné 1 , I. Mahé 3 , C. Font 4 , O. Sanz 5 , J.M. Martín-Antorán 6 , F. Pace 7 , J. Ramón Vela 8 , M. Monreal 9 1 Lucien Neuwirth Cancer Institute, Radiation Oncology, St Priest en Jarez, France 2 CHU Saint-Etienne, Vascular and Therapeutic Medicine, St Priest en Jarez, France 3 Hopital Louis Mourier, Internal Medicine, Colombes, France 4 Hospital Clínic de Barcelona, Medical Oncology, Barcelona, Spain 5 Hospital Universitario de Gran Canaria Dr. Negrín, Internal Medicine, Las Palmas, Spain 6 Hospital Río Carrión, Haemostasis and Thrombosis, Palencia, Spain 7 Ospedale San Camillo, Medicina d´Urgenza, Rome, Italy 8 Hospital Universitario Miguel Servet, Internal Medicine, Zaragoza, Spain 9 Hospital Universitari Germans Trias i Pujol, Internal Medicine, Barcelona, Spain Purpose or Objective There is lack of evidence on the influence of radiation therapy (RT) on outcome in cancer patients with acute venous thromboembolism (VTE). Material and Methods RIETE (Registro Informatizado Enfermedad Trombo Embólica) is an ongoing, multicenter, observational registry of consecutive patients with symptomatic, objectively confirmed, acute VTE. We used the RIETE database to compare the rate of VTE recurrences and

Conclusion eContour has a high rate of repeat use especially among radiation oncologists in the US. Users are most frequently looking for help contouring GI and H&N cancers, and they spend fewer than 4 minutes accessing information within a single case. These preliminary data suggest that eContour is a resource that fills a need among radiation oncology professionals. By providing users with updated contouring guidelines at the point of care, eContour has the potential to improve contour accuracy and ultimately impact quality of radiation delivery. PO-0752 Birth outcomes in female cancer patients received radiotherapy: a nationwide population-based study W.H. Kao 1 , J.H. Hong 1,2 , C.C. Wang 1,2 , Y.J. Chiang 1 , C.F. Kuo 3 1 Chang Gung Memorial Hospital, Department of Radiation Oncology, Taoyuan, Taiwan 2 College of Medicine- Chang Gung University, Department of Medical Imaging and Radiological Sciences, Taoyuan City, Taiwan 3 Chang Gung Memorial Hospital, Department of Poster: Clinical track: Other