ESTRO 36 Abstract Book
S649 ESTRO 36 _______________________________________________________________________________________________
Material and Methods Between June 2010 and March 2016, 25 patients with locally advanced breast cancer, who underwent modified radical mastectomy, IR, and PMRT were treated at our center. RT was delivered to the chest wall ± nodal areas according to stage, with 6MV and total dose of 50 Gy in 25 fractions. Complications were scored following the CTCAE 4.0 criteria. The capsular contracture was evaluated following the Baker classification. Cosmesis was rated as either acceptable or unacceptable to the patient. Results The mean age was 46.7 years (range, 33-65). A total of 20 patients underwent tissue expander and 5 underwent implant (TE/I). Median follow-up (from the start of RT) for all patients was 18 months (m) (4-48m). 40% of the patients were never smokers; 28% were smokers and 32% ex-smokers during RT. 10% and 68% of the patients received neoadjuvant and adjuvant chemotherapy respectively, and 17 patients taking Tamoxifen during RT. After surgery the complications occurred in 15/25 patients: 7 with capsulitis grade (G) 2; 2 with capsulitis G3-4; 3 with cutaneous suffering and mastitis, extrusion and hematoma were presented in 1 patient each. Complications post surgery in 2 patients as were hematoma and extrusion required additional surgery and delayed beginning of RT. All patients completed the RT course without major complications. During RT the only complication presented was skin erythema (SE) G1-2 seen in 20 (80%) and G3 in just 5 patients which were all smokers. During the follow up the major complications were: capsulitis G3 in 5 patients and G4 in 1; skin hyperpigmentation was presented in 4 patients, cutaneous thinning in 6 and 1 patient presented relevant lung toxicity. At the end of the follow-up, TE Exchange have been realized in 12 patients with a mean time after RT of 14,3m (9-22), 3 of them are pending of a new corrective surgery, specialy for improve cosmetic outcomes. We reported capsulitas G4 in 2 patients after the Exchange; both were smokers and 1 of them presented extrusion before RT, therefore she was operated twice. Acceptable cosmesis was reported in 60% of the patients Conclusion Our experiences is limited but in our patients undergoing PMRT, RT can be safely delivered after IR, with a low complication rate and good patient satisfaction. In our patients major complications occurred before RT. Further studies are needed to define the factors that may be related to worse aesthetic results. EP-1198 Low risk breast cancer patients' supportive care needs and perceptions of follow-up care options J. Kwan 1 , J. Croke 1 , J. Bender 2 , T. Panzarella 1 , K. Ubhi 1 , F. Liu 1 , A. Fyles 1 , A. Koch 1 , R. Dinniwell 1 , W. Levin 1 , D. McCready 3 , C. Chung 1 1 Princess Margaret Cancer Centre- University Health Network/ University of Toronto, Radiation Oncology, Toronto, Canada 2 University Health Network, ELLICSR Cancer Survivorship Centre, Toronto, Canada 3 Princess Margaret Cancer Centre- University Health Network/ University of Toronto, Surgical Oncology, Toronto, Canada Purpose or Objective Breast cancer is the most common cancer in women and survival following treatment is rising. Although traditional follow-up care has been by oncology specialists post- treatment, literature over the last decade has shown that non-specialist follow-up care is a safe alternative for early-stage breast cancer patients. Barriers in transitioning patients from oncologist follow-up have not been well characterized. This study aims to assess i) the existing follow-up practices at a large institution, ii) met
and unmet supportive care needs, and iii) patient views on alternative care models, particularly involving primary care and eHealth. Material and Methods A cross-sectional survey of well breast cancer patients attending radiation oncology follow-up appointments from August 2012 to May 2013 at the Princess Margaret Cancer Centre (Toronto, Canada) was completed. Eligibility criteria included English-speaking patients with T2 or lower tumor stage, node negative status, and ER/PR- positive breast cancer treated with radiation. Four domains were assessed: health care service use, supportive care needs, perceptions of follow-up care options, and internet usage. Descriptive statistics were completed for all variables and univariable analyses were performed to examine relationships between key variables and domains. Results Response rate was 80% (191/259). Respondents had a mean age of 60 (SD=10.6). Median time since first follow- up was 21 months. The majority of respondents (161/191; 84%) received follow-up care from greater than one cancer specialist and had a median of 3 health care professional visits per year. The most preferred follow-up model was specialist care at a tertiary centre (178/191; 93%) and the least preferred models were specialist care through video conferencing (29/191; 15%) and email (28/191; 15%). Shared care models involving a specialist and family physician were modestly accepted (103/191; 54%). Primary care only follow-up was not well accepted (35/191; 18%), particularly among patients with higher education. Respondents who reported few unmet supportive care needs (p=0.01) or who search online for health information (p=0.02) were more likely to report perceived satisfaction with specialist follow-up via eHealth. Conclusion Specialist health care services continue to be utilized by early-stage breast cancer patients during the post- treatment period. Transitioning patients to alternative follow-up models may be difficult due to strong patient preference for specialist care. Based on this survey, a minority of patients are willing to accept shared care with family physicians or eHealth follow-up via videoconferencing or email at this time. EP-1199 Radiotherapy for pN2 EGFR wide type adenocarcinoma & Squamous Cell Carcinoma lung cancer S.Y. Wu 1 1 Taipei Medical University Hospital, No.111- Section 3 Department of Radiation Oncology, Taipei, Chinese Taipei Purpose or Objective There is a lack of large, prospective, randomized studies comparing postoperative radiotherapy (PORT) in pathological N2 (pN2) and surgical resection alone in terms of long-term survival in the setting of lung adenocarcinoma (adenoCA; wild-type [WT] epidermal growth factor receptor [EGFR]) and squamous cell carcinoma (squCA). This national cohort study clarifies the role of PORT in the survival of pN2 lung adenoCA (WT EGFR) and squCA. Material and Methods We analyzed data of patients with adenoCA (WT EGFR) and squCA collected from the Taiwan Cancer Registry database. The patients were categorized into five groups according to the treatment modality: Group 1, comprising Electronic Poster: Clinical track: Lung
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