ESTRO 38 Abstract book

S1216 ESTRO 38

developed grade 3 radiodermatitis. The QoL was directly proportional to the initiation of radiodermatitis. Local discomfort lead to insomnia, anguish and mild depression, with more pronounced depressive episodes in women aged 32-40 years. Five patients presented with skin telangiectasia. While irradiation-induced fatigue together with the above adverse events decreased their QoL on the short term, 6-month post-therapy radiodermatitis has cleared, leaving only a light depigmentation on the breast skin. All patients confirmed an increased QoL with the disappearance of dermatitis. Conclusion There is a clear dependence between radiodermatitis and breast cancer patients’ QoL. The impact of adverse events on QoL can be diminished with the supportive care of the radiation therapists and physicians. The role of thermoplastic mask to reduce positioning errors and increase the therapeutic index outweighs the risk of adverse events and their impact on QoL. EP-2205 Patient involvement in developing research- based patient information on proton therapy A. Kristensen 1 , H. Hansen 1 1 Aarhus University Hospital, Danish Centre for Particle Therapy, Aarhus N, Denmark Purpose or Objective No previous patient information material on proton therapy has been developed in a Danish setting. A new centre for particle therapy is currently being established, and patient involvement is a fundamental value both during this process and will be in the future running of the centre. The purpose of this project was:  To test whether patient involvement as a method can be used in the development of research-based patient information.  To identify possible differences in patient information aimed at children, adolescents and adults. Material and Methods Qualitative semi-structured interviews were conducted with seven adults (18-55 years) and eight families with children and adolescents (2-18 years). The adult interviewees and the children/adolescents had received proton treatment abroad within the last two years. Qualitative content analysis inspired by Ricoeur was used to analyse the collected data. The emerging themes were discussed by the authors and consensus was reached. To ensure compliance between interview data and the actual patient information material and to ensure the quality, a user panel consisting of some of the interviewees will organised. Results The following main themes needed to be covered in the patient information:  The difference between proton and photon therapy; what protons are and when protons are preferred.  Illustrations of the equipment used in the treatment, making of the mask, how scans and treatment are performed as well as arguments for deliberately planning sometime between first visit and start of treatment.  Knowledge about possible side effects and their effect on the patient's life during and after end of treatment.  Information about practical issues (transportation and accommodation during course of treatment). Conclusion Patient involvement as a method is useful to ensure representation of the patient perspective when developing research-based patient information.

EP-2206 How long should men abstain from receiving anal sex following treatments for prostate cancer? S. Ralph 1 , C. Richardson 2 1 NHS, The Clatterbridge Cancer Centre NHS Foundation Trust, Bebington, United Kingdom; 2 University of Manchester, Division of Nursing- Midwifery and Social Work, Manchester, United Kingdom Purpose or Objective To develop UK guidance on how long men should abstain from receiving anal sex before, during, and after investigations and treatments for prostate cancer. Material and Methods A modified Delphi technique utilising two question rounds was employed in order to generate consensus opinion from a panel of 15 clinical oncologists and 11 urological surgeons who specialise in the diagnosis and treatment of prostate cancer. Results The overwhelming consensus from panel members was yes men should abstain from receiving anal sex before, during, and after investigations and treatments for prostate cancer (table 1). The consensus and consensus level for how long should men abstain was: 1 week before a PSA test (n=15 / 58%); 2 weeks after a transrectal ultrasound guided biopsy (n=6 / 55%); 1 week after a transperineal biopsy (n=6 / 60%); 6 weeks after a radical prostatectomy (n=5 / 45%); yes during external beam radiotherapy (n=11 / 73%) and for 2 months after (n=4 / 40%); and 2 months after high-dose rate brachytherapy (n=3 / 60%). Panel members failed to reach consensus on how long men should abstain from receiving anal sex after the insertion of fiducial marker and permanent seed brachytherapy. Conclusion Men should abstain from receiving anal sex before, during, and after investigations and treatment for prostate cancer in order to avoid receiving a false positive PSA test; manage their side effects appropriately; minimise radiation exposure to sexual partners; and to minimise the risk of developing post-intervention complications. The data from this study has been used by the charity Prostate Cancer UK to update their patient information publication ‘Prostate cancer tests and treatment: A guide for gay and bisexual men’. EP-2207 PROMs: Transperineal insertion of prostate markers – results from a prospective clinical trial A. O'Neill 1,2 , K. Crowther 1 , D. Mitchell 1 , S. Jain 1,2 , A. Hounsell 1,2 , J. O'Sullivan 1,2 1 Belfast Health and Social Care Trust, Radiotherapy, Belfast, United Kingdom; 2 Queens University Belfast, Centre for Cancer Research and Cell Biology, Belfast, United Kingdom Purpose or Objective Surgical insertion of fiducial markers (FMs) is an important component of image guided radiotherapy for prostate cancer and has similar risks to that of prostate biopsy including pain, bleeding, and infection. The procedure is usually performed on an outpatient day case basis using a transurethral ultra-sound (TRUS). We report our experience of FM insertion and patient feedback on acute effects from a prospective clinical trial.