ESTRO 38 Abstract book

S753 ESTRO 38

From 2015 to 2017, 100 survivors were asked to participate in the event. 51 patients (51%) agreed to participate but only 19 (19%) patients were present. Baseline mean anxiety and depression level were 15.8 (scale 0-25, where the highest score corresponds to the lowest level of anxiety) and 11.83 (scale 0-15, where the highest score corresponds to the lowest level of depression) respectively. Only 25% of patients reported high level of anxiety. Only one patient (8%) showed severe depression. No change was detected three months after the event. Almost half of patients presented pain at baseline (56%) while 38% of patients experienced fatigue. Pain and fatigue improvement after the event occurred in 4 patients (27%). Most of patients reported healthy habits (67-100%). Improvement in dietary habits after the event was also reported (5-10%). Conclusion Only few patients participated in the event. However information provided during the event led patients to modify their habits. Through the questionnaires we were able to identify subgroups of survivors with severe anxiety and depression to whom dedicate intervention strategies Intra-fraction motion was monitored in 76 fractions of 15 patients with lung SBRT. In 9 patients, 4D-CT scans were acquired into consideration in consideration of all phases of respiration, and ITV was created by adding a margin depending on the amount of motion of the GTV. PTV was created by including safety margins in ITV. Prior to the treatment, 4D-CBCT scanning was performed to ensure the accuracy of the target and patient position. Then, while the VMAT field was irradiated, CBCT scanning was performed simultaneously. After the treatment field was completed, the amount of motion in the target was determined. In this way, intra-fraction motion was monitored in 51 fractions of 9 patients. For the 6 patients with the catalyst surface scanning system, breath was restricted in the determined phase range (deep breath) of the respiration and a CT scan was performed. PTV was created by adding only one safety margin to the GTV, despite limited respiratory in patients scanned by DIBH- CT. Prior to the treatment, CBCT scanning was performed to ensure the accuracy of the target and patient position. Then, while the VMAT field was irradiated, CBCT scanning was performed simultaneously. After the treatment field was completed, the amount of motion in the target was determined. In this way, intra-fraction motion was monitored in 25 fractions of 6 patients. Results The mean deviation (± direction) during treatment was 4 cm with 4D-CT and 0.13 cm with DIBH-CT. In 76 fractions of 15 patients, the maximum deviation was obtained smaller than 0.3 cm. A deviation of greater than 0.3 cm was obtained with the DIBH-CT on the vertical axis and 4D- CT on the longitudinal axis (Table1). EP-1380 Intra-fractional Motion in Lung SBRT Treatments with Different IGRT Techniques I.F. Durmus 1 , B. Tas 1 , A. Okumus 1 1 Yeni Yuzyil University Gaziosmanpasa Hospital, Department of Radiation Oncology, istanbul, Turkey Purpose or Objective Investigation of intra-fraction in 4D-CT and DIBH-CT techniques in lung SBRT treatments. Material and Methods

Chi-square for trend p=0.0015

104 patients underwent follow-up imaging at a median of 49(IQR 22.5-87.5) days from end of treatment. During the follow-up period 56(51%) patients experienced distant relapse, of which 18(32%) had BM. Distant relapse occurred within 3 months of the end of treatment for 11 patients, of which 2 patients were diagnosed with BM. The median overall survival of patients relapsing with BM was 5.9 months(95% CI: 2.9-13.1) and with other site of relapse was 5.9 months(95% CI: 4.1-8.6).(See figure)

Conclusion Our study shows that clinicians have increasing awareness of the need for pre-treatment brain imaging in cN2 patients for radical treatment. This can still be improved further. After CRT, one third of patients relapsed with symptomatic BM for whom survival was poor. Progress in BM treatment warrants investigating the impact of routine follow up brain imaging after treatment. EP-1379 RE-STARTing after lung cancer: impact of a wellbeing event on global health status of survivors. E. Ippolito 1 , M. Fiore 1 , C. Greco 1 , S. Silipigni 1 , B. Floreno 1 , M. Miele 1 , B. Santo 1 , L. Trodella 1 , R.M. D'Angelillo 1 , S. Ramella 1 1 Campus Biomedico University, Radiotherapy, Roma, Italy Purpose or Objective Modern therapies led to an increased survival for patients with lung cancer. Therefore there is a need for dedicated survivorship care for these patients. The aim of this study was to investigate the impact of one day wellbeing event (RE-START initiative) on their health and QoL. Material and Methods Patients with primary lung cancer treated in our institution, after the completion of cancer treatment and in clinical remission were asked to participate in the event. During the event, there were talks providing information on diet, keeping active and managing stress. During the event participants completed a survey package that included the Psycological General Well Being Index (22 items) for distress assessment, NCCN Survivorship Assessment for physical wellness evaluation (14 items), World Cancer Research Fund Cancer Risk derived questionnaire for Dietary and Lifestyle Habits (11 items). The same survey package was completed 3 months after the event by phone interviews. Results