ESTRO 38 - Programme Book & Exhibition Guide

SYMPOSIUM Biological Imaging for Radiotherapy 14:30 - 15:45 | Brown 1

MONDAY 29 APRIL 2019

Exciting, new imaging techniques based on PET and MRI for visualizing tumor biological features in the context of radiotherapy have emerged. Promising PET approaches for imaging of DNA damage responses using γH2AX and PARP radiotracers and to visualize infiltration of T-cells and tumor hypoxia will be discussed. Moreover, the MRI-Chemical Exchange Saturation Transfer (CEST) method and its potential for imaging of tumor acidosis will be present-ed.

Chair: H. Lyng (Norway) Co-chair: A. Bunea (Switzerland)

14:30 > Imaging of tumor infiltrating lymphocytes with [18F] FB-IL2 PET Speaker: E. De Vries (The Netherlands), S. Hartimath, O. Draghiciu, V. Manuelli, A. Van Waarde, R. Dierckx, T. Daemen, H. Nijman

SP-0553

14:48 > Imaging DNA damage response

Speaker: B. Cornelissen (United Kingdom)

SP-0554

15:06 > MRI-CEST Imaging of tumor acidosis Speaker: D. Longo (Italy)

SP-0555

15:24 > Tracing Tumor Hypoxia

Speaker: M. Vooijs (The Netherlands), J. Ient, A.J. Groot, J.A.F. Vermeer, R. Muschel, J. Van Rheenen, D. Postrach, B. Markelc

SP-0556

SYMPOSIUM New developments for breast cancer irradiation 14:30 - 15:45 | Gold Plenary

The management of breast cancer is multidisciplinary from the time of initial cancer diagnosis. Recently introduced systemic therapies (e.g., anti-HER2) and surgical techniques (e.g., oncoplasty, reconstruction, selective lymph node dissection) are being progressively introduced into daily practice. Parallel to that, the radiation techniques improved which allows for volume-based radiation therapy. Therefore, it is time to move forward volume-based delineation and more precisely define the target volumes with the highest risks for harbouring subclinical disease. This approach is necessary to solve issues of improved dose coverage and lowered normal tissue toxicity, thereby allowing for irradia-tion in cases that in the past was associated with increased toxicity (e.g., preoperative, after reconstruction). This concept also supports decreasing doses and

SCIENTIFIC PROGRAMME | Programme and Exhibition Guide

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