ESTRO 38 - Programme Book & Exhibition Guide

INTERDISCIPLINARY RADIOBIOLOGY CLINICAL BRACHYTHERAPY PHYSICS RTT YOUNG

MONDAY 29 APRIL 2019

08:45 > Opposition and opportunity for immunotherapy via the irradiated tumor microenvironment Speaker: MH Barcellos-Hoff (United States) 09:03 > Radiotherapy and cisplatin increase immunotherapy efficacy by enabling local and systemic intratumoral T-cell activity Speaker: P. Kroon, E. Frijlink, V. Iglesias-Guimarais, A. VOLKOV, M. Van Buuren, T. Schumacher, M. Verheij, J. Borst, I. Verbrugge (The Netherlands) 09:21 > Targeting DNA repair to improve immune-surveillance and restrict cancer growth Speaker: G. Germano (Italy), S. Lamba, G. Rospo, L. Barault,

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A. Magrì,,F. Maione, M. Russo, F. de Braud, S. Marsoni, M. D'incalci, A. Sartore-Bianchi, S. Siena, F. Pietran-tonio, F. di Nicolantonio, A. Bardelli

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09:39 > Trial design: early clinical studies and learning from the laboratory Speaker: T. Illidge (United Kingdom)

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SYMPOSIUM Tumor Metabolism and Radiotherapy 08:45 - 10:00 | Brown 1

As tumors have a different regulatedmetabolism that drives tumor growth and influence treatment response, manipula-tion of the metabolism can potentially benefit different treatment modalities such as radiotherapy. In this session new approaches, insights and clinical promises to impair different aspects of the tumor metabolism, hypoxia tolerance and associated DNA damage will be discussed.

Chair: J. Bussink (The Netherlands) Co-chair: M. Van Gisbergen (The Netherlands)

08:45 > Inhibition of glycolysis and redox metabolic pathways in cervical cancer Speaker: J. Schwarz (USA) 09:03 > Sex differences in cancer metabolism: implications for therapy Speaker: J. Ippolito (USA)

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09:21 > Metabolic targeting of tumor cells Speaker: C. Pecqueur (France)

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09:39 > Targeting metabolism to sensitize hypoxic tumor cells Speaker: M. Koritzinsky (Canada)

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Programme and Exhibition Guide | SCIENTIFIC PROGRAMME

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