ESTRO 38 - Programme Book & Exhibition Guide

SYMPOSIUM Challenging dose painting: Are we really painting what we aim to or the better outcome is only linked to higher dose spots within the CTV? 10:30 - 11:45 | Auditorium Molecular imaging opens the possibility of defining areas within the GTV which due to a higher tumour burden or hypoxia would benefit from a higher radiation dose. Different trials on dose painting by volumes or numbers have been designed. At the same time interesting work on grid therapy, treating with high heterogeneous dose, has shown better outcomes in lung cancer. During this symposium, the different speakers will present: • Preclinical studies on dose painting. In particular comparison between dose escalation and dose redistribution based on FDG uptake in rat rhabdomyosarcoma model. • Evaluation of loco-regional control and toxicity of a prospective clinical trial with adaptive dose-painting-by-numbers for head-and-neck cancer. • Heterogeneous dose adaptation of treatments, based on treatment response for cervix cancer patients. • The role of multi-modal imaging and its sensitivity and specificy to prescribe the optimal dose using simultaneous integrated boost or dose painting. 10:30 > What is left from dose painting when adding all uncertainties Speaker: M. Alber (Germany) 10:48 > What are the limitations on dose escalation to sub-volumes in head and neck cancer: experience from dose painting Speaker: F. Duprez (Belgium) 11:06 > Heterogeneous dose adapted to treatment response during radiotherapy: clinical experience from cervix cancer IGABT Speaker: I. Jürgenliemk-Schulz (The Netherlands) 11:24 > Exploiting low drug uptake volume for dose painting Speaker: A. Yaromina (The Netherlands) Chair: N. Jornet (Spain) Co-chair: E. Troost (Germany)

SATURDAY 27 APRIL 2019

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SP-0051

SP-0052

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SCIENTIFIC PROGRAMME | Programme and Exhibition Guide

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