ESTRO Brachytherapy for Prostate Cancer 2018

Radiation proctitis - Acute Pathophysiology Histopathology findings • Transient mucosal atrophy • Submucosal oedema • Inflammation and infiltration of the lamina propria with polymorphonuclear leukocytes and plasma cells • In addition, mitotic arrest, karyorrhexis, and lysis of the crypt and deep epithelial cells