ESTRO Multidisciplinary Management of Breast Cancer 2017

Short and long term side effects aromatase inhibitor

Most commonly reported symptoms Menopausal symptoms • Musculoskeletal symptoms (AIMSS) • Arthralgias incidence is 40%, 15-20% reason for treatment discontinuation • Myalgias, tendonitis, and carpal tunnel syndrome • Vaginal dryness and decreased libido • Hot flushes Osteoporosis BMD -6 à 7% after 5 year compared to tamoxifen (+1 à 2%)

19-9-2017