ESTRO Multidisciplinary Management of Breast Cancer 2017

Tamoxifen (5y) vs no Tamoxifen

Endometrial cancer Relative risk: 2.40 ( p<0.00002)

Thrombo-embolic disease/Vascular mortality Little net effect on overall vascular mortality Relative risk trombo-embolic disease: 2.50 (p: 0.07)

Overall, the absolute risk of death for both endometrial cancer and vascular complications is 0.2% in ten years ( ECCTCG 2005)

EBCTCG, Lancet 2005 EBCTCG, Lancet 2011