ESTRO Multidisciplinary Management of Breast Cancer 2017

Cosmetic results after breast conserving therapy

• Which factors play a role ? Several RCTs to investigate impact of:

Factor studied

Impact on cosmesis

Conclusion

Hypofx

No change in breast appearance

No boost vs low boost

No boost better than boost

Hypofx: Whelan 2008; Haviland 2013; Prone vs supine: Veldeman 2016; 2D CRT vs IMRT: Pignol 2016; Mukesh 2014; No vs low boost: Vrieling 1999 & 2000, Hau 2013; Low vs high boost : Brouwers 2016; PBI vs WBRT: Polgar 2017, Coles 2017, Peterson 2015