ESTRO Multidisciplinary Management of Breast Cancer 2017

Phase III: Boost for DCIS: BONBIS Trial (France)

WBRT (50Gy)

Randomization

WBRT + Boost (16 Gy)

N=1 950 DCIS

• •

Closed

• Designed to detect a difference of 7% vs. 4%- • Planned analysis based on number of IBTRs