ESTRO Multidisciplinary Management of Breast Cancer 2017

Impact of Oncoplastic Surgery on Survival and Local Recurrence. Case series

• Mansell et al, 2017, compared LRR at 5 years between standard WLE, OPS and Mastectomy with LRRs of 3.4, 2 and 2.6% respectively (P = NS) despite WLE cases being smaller and less adverse histologically. • DFS rates of OPS and Mastectomy were similar in keeping with their similar stage and grade profiles

• Large series report 5 year rates of LRR 4%. Overall Survival rate 94.5% and DFS of 90.9% (Rezai et al, 2014). • Lee et al, 2017, compared surgery types and 6 year LRR, OS and DFS and found no significant difference by surgery type.

A large meta analysis (De La Cruz et al, 2016) confirmed that there is no LRR, DFS or OS disadvantage compared to case matched standard BCS or mastectomy