ESTRO Multidisciplinary Management of Breast Cancer 2017

Overview of studies on effect of RT on breast recurrences in DCIS • 3 large meta-analyses

• Meta-analysis EBCTCG (2010), N = 3729: Lumpectomy +/- RT: • Individual patient data of 4 RCTs

• Meta-analysis Stuart et al (2015), N = 9404: Lumpectomy +/- RT: • Analysis of published data: 3 RCTs, 2 prospective and 21 retrospective series

• Meta-analysis Garg et al (2017), N = 3680, Lumpectomy +/- RT: • Meta-analysis of 4 published RCTs with longterm follow-up