ESTRO Multidisciplinary Management of Breast Cancer 2017

Summary 1

• Consistent evidence that positive margins result in higher LRR, regardless of • Tumour biotype • Age • Systemic Treatment • Boost

• Uncertainty regarding whether residual disease is present or not or whether it is small volume (and likely to respond to RT/CT) or large volume. • Data shows that local recurrence at 5 years translates into increased mortality rates at 15 years (EBCTCG)