ESTRO Multidisciplinary Management of Breast Cancer 2017

What happens if you accept focally involved margins ?

Results in the Netherlands:

• Dutch Cancer Registry, 2003-2006: N = 22.450 • Boost only given if Risk Factors like G3, LVI, Age < 50 yr, or Focally involved margins • 5 yr IBTR : 2.38% (2.18-2.60%) Van der Heiden et al, Ann Oncol 2015

• NKI/AVL, 1980-2008 : N = 8485 • 5 yr IBTR: 2% ( if < 40 yr: 4%) • 10 yr IBTR: 5% (if < 40 yr: 9%)

Bosma et al, Br C Res Tr 2016