ESTRO Multidisciplinary Management of Breast Cancer 2017

Theoretical concept of the Clinical Target Volume for the boost

• CTV for the boost: – The rim of breast tissue – that has been localized < 1.5 - 2 cm around the primary tumor. – Margin of 1.5 - 2 cm is debatable – e.g.< 3.0 cm in case of PBI (Kirby et al, R&O 2010). • Delineation is dependent on the post-op situation; 3 post-operative situations can be recognized: – Clear seroma cavity present – No seroma cavity present – Partial seroma cavity present