ESTRO PT 2018

Overall Survival Curves of locally recurrent rectal cancer by primary CIRT and CIRT as reirradiation

0 10 20 30 40 50 60 70 80 90 100

Reirradiation (n=47)

Primary (70.4GyE) (n=22)

Survival Rates(%)

0

10

20

30

40

50

60

Time(months)

Local Control

5y-Survival

Author

Year

N

Total Dose

ToxicityG3

34

Surg 22%

70-108Gy (85.8Gy)

Acute 4% Late 26% Acute 4% Late 26% Acute 17% Late 25%

Number

1y

3y

5y

Modiuddin M 2002

44%

69

15%

47

87.6% 71.2% 29.5%

Reirradiation

18

Surg 44%

Das P

2010

64-109Gy(86Gy)

Primary （ 70.4GyE)

32

12%

22

77.3% 43.8% 21.5%

90-140GyE (118GyE)

NIRS

2014 47

30% 81% (5y)